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Glycomics Hits the Big Time
Cells run on carbohydrates. Glycans, sequences of carbohydrates conjugated to proteins and lipids, are arguably the most abundant and structurally diverse class of molecules in nature. Recent advances in glycomics reveal the scope and scale of their functional roles and their impact on human disease.
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When it comes to structural biology, bigger really is better. Most biological processes are performed by enormous multicomponent complexes, such as the ribosome. To solve the structures of these monsters, biologists traditionally have used two different but complementary techniques, nuclear magnetic resonance (NMR) and X-ray crystallography. They have had considerable success using the latter t...
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T here aren't many sports articles in the journal Science, so it was with great interest that I read " A Late Hit for Pro-Football Players " by Greg Miller (www. sciencemag.org). 3 This article is a very interesting compilation of recent research and developments in the area of sports-related concussion. The article highlights the efforts of Chris Nowinski, a former Harvard football standout wh...
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The growth in complexity of the World Wide Web, matched by the increase in user sophistication, has transformed the notion of user disorientation. While the retrieval of visited Web pages has been studied, the particular class of Web pages not initially recognized as being important enough to return to merits closer examination. Such pages, referred to as Post-Valued Recall (PVR) Web pages, ten...
متن کاملBig hits on the small screen: an evaluation of concussion-related videos on YouTube.
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ژورنال
عنوان ژورنال: Nature
سال: 2003
ISSN: 0028-0836,1476-4687
DOI: 10.1038/425028a